Week Ending September 12, 2022

Larotrectinib Demonstrates Robust Responses in TRK Fusion-Positive Lung Cancer
“The treatment landscape for NTRK fusion-positive disease has been evolving with developments of new tyrosine receptor kinase (TRK) inhibitors for this patient population.”

Lung Cancer Insurance Coverage: Potential Barriers
“A lung cancer diagnosis doesn’t just affect a person physically and emotionally. Costly tests and treatments can also put a strain on your finances, even if you have health insurance coverage. These unanticipated costs can be a source of stress and may discourage patients from pursuing potentially lifesaving treatment options.”

Q and A: How early should I be screened for lung cancer?
“I am 62 and recently had a physical. My doctor suggested that I should be screened for lung cancer. I used to smoke a pack of cigarettes a day but quit about a decade ago. I’ve not had any problems, so I’m wondering if this is necessary. What does screening involve?”

Does Smoking Cause Small Cell Lung Cancer?
“Small cell lung cancer (SCLC) is an aggressive form of lung cancer predominantly caused by cigarette smoking, making up 13% of all U.S. cancer cases.”

Recommendations to Safeguard Quality Shared Decision-Making for Lung Cancer Screening
“An international group of researchers, practitioners, and stakeholders involved in advocating for high-quality shared decision-making tools used by providers and patients issued 2 recommendations Thursday in response to an updated national coverage determination (NCD) about lung cancer screening released earlier this year by CMS.”

Q&A: Biomarker testing opens doors for personalized treatment options in lung cancer
“Biomarker testing in patients with lung cancer allows for the potential of personalized therapy options that may be better tolerated and increase overall survival, yet not all patients undergo testing.”

Study Results Link Lung Cancer Screening Guideline Changes to Racial Disparity Reductions
“Changes in 2021 to the US Preventive Services Task Force (USPSTF) lung cancer screening guidelines were associated with reductions in existing eligibility disparities in lung cancer screening among Black and white individuals but not the elimination of disparities, new study results showed.”

Study Finds Particulate Matter May Drive EGFR-Positive Non-Small Cell Lung Cancer
“Findings provided rationale to limit air pollution and highlighted the need for molecularly targeted lung cancer prevention due to particulate matter being revealed as a mechanistic driver for EGFR-positive NSCLC.”

The treatment landscape for NTRK fusion-positive disease has been evolving with developments of new tyrosine receptor kinase (TRK) inhibitors for this patient population.

Dr Hatim Husain: NCCN Guidelines Adjust to Meet Lung Cancer Treatment Needs