Surgery for Lung Cancer Patients
Maria Cattoni, MD, Lisa M. Brown, MD, MAS, Ben M. Hunt, MD, MSc,
and Brian E. Louie, MD, MHA, MPH, FRCSC, FACS
Surgery is one of the main options for treating patients who are diagnosed with lung cancer. Sometimes surgery is the only treatment necessary, and sometimes surgery is combined with chemotherapy and/or radiation therapy. It is not always easy to determine which treatment or combination of treatments may be necessary. Therefore, meeting with a surgeon who is specially trained in lung surgery is an important step in the management of lung cancer.
Many patients are nervous about surgery. We hope that this chapter will prepare the patient and his or her support team for meeting with a surgeon and for surgery. This chapter has been divided into seven sections to address the following questions:
- What types of surgery are used to treat lung cancer?
- How do I prepare for surgery?
- What can I expect the day of surgery?
- What can I expect during the hospital stay?
- What is the recovery from lung surgery like?
- Am I cured?
When Surgery is Used to Treat Lung Cancer
Surgery for Non-Small Cell Lung Cancer
Non-small cell lung cancer includes several different subtypes (Figure 1), but the treatment for all these subtypes is similar. After a person is diagnosed with non-small cell lung cancer, the decision to proceed with surgery is based on two factors: (1) the stage of the cancer and (2) the ability of the patient to function without the cancerous portion of lung. We will discuss these two factors in the next two sections of this chapter.
Figure 1: Lung Cancer, as seen through the microscope
Images courtesy of Jey-Hsin Chen, MD, PhD
Figure 1: A: Small cell carcinoma. B: Squamous cell carcinoma. C: Adenocarcinoma. D: Adenocarcinoma with lepidic features. B, C, and D are all different types of non-small cell lung cancer
Lung Cancer Staging from the Surgeon’s Perspective
After a diagnosis of lung cancer has been made, the most important question is, “How far has it spread?” This process is called staging. This is first determined by using imaging tests such as a positron emission tomography (PET) scan and/or a computed tomography (CT) scan. From these tests the surgeon can determine the location of the cancer and whether the cancer is confined to the lung or has spread to other areas in the body such as lymph nodes, the other lung, the brain, or other organs. These findings allow the surgeon to classify the cancer into one of four groups called “stage” (stage I, stage II, stage III, stage IV).
Usually the combination of chest computed tomography scan (CT) and positron emission tomography (PET) are enough to determine the location and dimension of the lung cancer and whether it has already spread to other areas of the body as the lymph nodes, the liver, the bones and the adrenal glands. However, if there is concern on the PET scan that lymph nodes may be involved, the surgeon usually will order a magnetic resonance imaging (MRI) to assess whether cancer is present in the brain.
Even though the PET, CT and brain MRI are very good at detecting the spread of lung cancer to the liver, the bones, the adrenal glands and the brain, there is an 8-10% chance of missing cancer in the lymph nodes in the center of the chest (Figure 2: the mediastinum). Since determining the presence of cancer in the mediastinal lymph nodes is necessary to define the cancer stage, it is important to know more definitely whether the cancer involves the mediastinal lymph nodes. Therefore, a biopsy (a small tissue sample) of the mediastinal lymph nodes is usually recommended before lung cancer surgery.
Mediastinal lymph nodes may be biopsied in several different ways. The two most common ways are (1) with a bronchoscope (a flexible camera that is inserted through the windpipe) and ultrasound imaging guiding a small needle or (2) an operation (mediastinoscopy). During mediastinoscopy, a surgeon makes a small incision in the neck just above the breastbone and puts a camera behind the breastbone to take tissue samples of the mediastinal lymph nodes around the windpipe. (Figure 3)
Figure 2: Mediastinum
Illustration by Alexandra Hunt, MD
Figure 2: The green-shaded area is the mediastinum. Purple dots around the airways are the mediastinal lymph nodes.
Figure 3: Mediastinoscopy
Illustration by Alexandra Hunt, MD
Figure 3: Mediastinoscopy: a scope and instruments are used to sample the mediastinal lymph nodes.
If the biopsy of the mediastinal lymph nodes shows no cancer, then we presume the patient to be in stage I or II and recommend surgical removal of the lung cancer. However, if there are cancer cells in these lymph nodes, chemotherapy with or without radiation therapy usually is the first treatment, sometimes followed by surgery.
The importance of defining the cancer stage is due to the fact that lung cancer at different stages requires different treatment (Table 1). Surgery has a potentially curative role in non-small cell lung cancers that are stages I to III (Table 1) and in selected cases of stage IV lung cancer.
Table 1. Treatment of Lung Cancer by Stage1
|Stage||Defining characteristics||Common treatment options|
|I||Small tumor with no lymph node
|Usually surgery but radiation is an alternative. Sometimes followed by chemotherapy.|
|II||Larger tumor or lymph node involvement, but only lymph nodes within the affected lung||Usually surgery, usually followed by chemotherapy, sometimes radiation|
|III||Tumor very large or invasive, or lymph
node involvement in the central chest
|Usually chemotherapy and radiation, sometimes followed by surgery|
|IV||Distant spread||Usually chemotherapy, sometimes radiation therapy. Rarely surgery to relieve specific
Surgery usually is the first step in the treatment of Stage I and II non-small cell lung cancers. In Stage III cancers, chemotherapy with or without radiation therapy is given first and surgery follows if it will potentially be beneficial. The distinguishing feature between stages I, II, and III is the involvement of lymph nodes with cancer. In stage I, cancer has not spread to the lymph nodes. In stage II, the lymph nodes that are involved are located within the section of lung being removed. In stage III, the lymph nodes involved are outside of the lung and organized around the main airway in the center of the chest, in the area of the body called the mediastinum (Figure 2). When the cancer has spread to the lymph nodes in the mediastinum, surgery alone is not enough. In this case, studies have shown that chemotherapy with or without radiation therapy, sometimes combined with surgery, has a better outcome than surgery alone.
Surgery in Stage IV Cancer
If cancer has spread to distant sites, it may not be possible or beneficial to remove all the cancer with surgery. Additionally, if the cancer invades structures that cannot be removed (for example, the heart), then surgery may not be appropriate as primary treatment. However, there can be a role for surgery in widespread cancer if surgery will help relieve some of the symptoms caused by the cancer. If the cancer is blocking an airway, a limited procedure might be done to unplug the airway. When advanced cancer blocks the lymph channels draining the space around the lung, fluid can build up in this space. Surgery may be required to drain this space and re-expand the lung to relieve the symptoms associated with the fluid. However, most surgery for lung cancer is done for limited disease (lower stages), usually with the goal of curing the cancer. Occasionally, stage IV cancer that has spread to only a single location outside of the lung such as the brain or adrenal gland may be a candidate for surgical treatment of both the metastasis (the single cancer location outside of the lung) and the primary lung cancer. This special situation should be discussed with the cancer team (the surgeon, the oncologist and the radiation oncologist).
Even if lung cancer can be removed based on the results of the staging tests, not every person can have part of their lung removed and return safely to their normal life outside the hospital. Every operation has risks, and one of the difficult aspects of surgery is choosing which people will do well after surgery and which people will have difficulty recovering from surgery. Surgeons use many different tests to help predict which patient can undergo surgery safely and be able to live with fewer lung after surgery.
The most important test we use to decide when to operate is the simplest: a thorough history and physical examination. The surgeon asks questions about the patient’s current state of health and past medical history, and performs a physical examination to make sure the patient is prepared for the operation.
Problem areas that come up during the history and physical examination may be evaluated with more testing. There are two major issues to consider preoperatively: to make sure that the patient is healthy enough to safely have surgery, and to find any other health problems that can be improved before the operation. For example, diabetes should be well controlled before surgery since it impacts wound healing. It is also very important to stop smoking before lung surgery in order to reduce the risk of respiratory complications after surgery. See Chapter 11: How to Quit Smoking Confidently and Successfully. After dealing with each person’s individual health problems, the preoperative workup for lung surgery focuses on the lungs and the heart in order to evaluate the performance of these two organs.
Lung and Heart Function
Surgery for lung cancer usually involves removing part of a person’s lung. Therefore, it is important to be sure that the person will be left with enough functioning lung after surgery to provide oxygen to, and eliminate carbon dioxide from, the body. A simple test such as climbing stairs or walking as far as possible in six minutes may be used to give an overall idea of heart and lung fitness, but more detailed testing usually is required before lung surgery.
The tests most commonly used to evaluate the lungs before surgery are called pulmonary function tests. These tests check the lung volumes, air flows, and gas exchange capabilities. They give a baseline measure of lung function and help predict whether the lungs will be able to do their job adequately after part of the lung is removed during surgery. The tests are designed to measure how much air can be moved in and out of the lungs, and how quickly gases diffuse from the lungs into the blood. The tests involve breathing through a machine which measures air flow, and inhaling a marker gas (a very small amount of carbon monoxide) to test how quickly that gas is removed from the air in the lungs. It is important to stop smoking before the pulmonary function test, because blood levels of carbon monoxide are elevated after smoking and this can interfere with the test. Medication may be given during the test to determine whether lung function can be improved with medication.
If a person’s pulmonary function tests show limited lung function, then a quantitative ventilation/ perfusion scan (QV/Q scan) is used to determine how much air and blood flow go to each section of the lung. This allows the surgeon to calculate how much lung function will remain after the section of lung containing the cancer is removed, thus predicting how the person will respond to surgery. If concerns remain after the QV/Q test, the patient may be asked to have other testing, including exercise tests and blood tests. The purpose of all the lung function tests is to predict whether there will be enough lung function remaining to allow the patient to return to normal life after surgical removal of the part of the lung with the cancer.
Often it is also necessary to evaluate the patient’s heart before lung surgery because the risk factors for heart disease are often present in patients who develop lung cancer. Furthermore, surgery places the body under stress. The body mobilizes every resource available to heal after surgery, and this effort can place major stress on the heart, especially when an entire lung has been removed (pneumonectomy). Therefore, it is important to check that the heart is functioning adequately before performing an operation. In some cases, a history and physical examination can provide enough information to reassure the treatment team that the heart will be able to safely power the body through the stress of surgery. If further testing is required, it may be simply an electrocardiogram (ECG). Another test that might help predict how the heart will respond to the stress of surgery is a stress test, in which stress is placed on the heart by walking on a treadmill or by injecting a medication that stresses the heart. Imaging of the heart may include an ultrasound test or a scan. If any problems with the heart are found during testing, additional procedures or medicines may be required to make sure the heart is as ready as possible before surgery.
Alternatives to Surgery
If surgery is not recommended after the staging workup and heart and lung testing, there are several alternative treatments available. These treatments also may be used before or after surgery, to give the best chance that cancer will not spread to other parts of the body or recur in the lungs after treatment. Radiation therapy can be used to kill cancer cells in a particular part of the body. The radiation is focused at the known or suspected location of the cancer. New highly-focused radiation techniques allow maximum doses of radiation to be delivered precisely to the cancer, killing the cancer while sparing as much normal tissue as possible. In some people with stage I or II cancers with poor lung function, focused radiation may be recommended instead of surgery. Chemotherapy medicines, given either intravenously or as pills, kill cancer cells throughout the body. Chemotherapy medicines spread through the entire body, and they can kill cancer cells that haven’t been discovered or are too small to show up on imaging.
Surgery for Small Cell Lung Cancer
Small cell lung cancer is very different from non-small cell lung cancer. Small cell lung cancer tends to spread more quickly than non-small cell cancer, and surgery alone has a very small chance of curing small cell lung cancer, even in the early stages. Chemotherapy and radiation are the primary treatments for most small cell lung cancers. However, surgery may benefit a small group of patients with early small cell lung cancer, used in combination with chemotherapy, with or without radiation therapy. Surgical sampling of the lymph nodes from the middle of the chest is also part of the staging workup of small cell lung cancer if surgery is contemplated. See Chapter 1: Diagnosis and Staging of Lung Cancer and Chapter 5: Treatment for Small Cell Lung Cancer.
Types of Surgery to Treat Lung Cancer
Figure 4a: Thoracotomy: the blue line corresponds to the chest incision
Illustration by Alexandra Hunt, MD
To limit the pain and shorten the recovery after surgery, sometimes it is possible to do surgery without performing a full thoracotomy. One way to do this is to use a video camera that goes into the chest through a small incision, combined with instruments that enter the chest through other small incisions. This type of surgery is called video-assisted thoracic surgery (VATS) (Figure 4b). A further refinement of VATS is to mount the instruments to a robot (Figure 4c), which allows very precise control when manipulating the lung and delicate surrounding tissues. However, it is important to be aware that even if the surgeon plans to do the operation using the VATS approach or the robot, sometimes it is necessary to convert during the operation to a bigger incision (thoracotomy).
Figure 4b: Video-Assisted Thoracic Surgery (VATS) and robotic thoracic surgery incisions: the blue lines correspond to the chest incisions.
Illustration by Alexandra Hunt, MD
Figure 4c: Robotic thoracic surgeryIllustration by Alexandra Hunt, MD
Besides deciding on which approach will be used to remove the portion of lung containing the cancer, a surgeon must decide exactly what to remove. The first priority is to remove the cancer. It is important to remove some normal surrounding lung along with the cancer, because there are microscopic extensions of the cancer that can grow and cause cancer recurrence if they are not removed. The most common surgery for lung cancer removes the entire lobe containing the cancer, together with the lymph nodes inside the lobe (lobectomy, Figure 5a). Removing the entire lobe allows the best possibility for long term survival.2 However, recent studies have been evaluating whether the resection of the cancer within a smaller part of the lung (segmentectomy) has the same results, in term of survival and probability of cancer recurrence that occur when removing the entire lobe (lobectomy). The results of these studies will be available in the next years.
In patients where there will not be enough healthy lung left after an entire lobe is removed, the surgeon may decide to remove just the tumor with a small amount of surround lung called a (wedge resection) or a segment of lung (segmentectomy) that contains the cancer (Figure 5b). If the tumor is too close to the center of the chest, or if the main airways of the lung are involved, sometimes it may be necessary to remove the entire lung that is affected by cancer (pneumonectomy, Figure 5c). Airways may be divided and sewn back together (“sleeve resection”), if this allows complete removal of the cancer without removing as much healthy lung tissue (Figure 5d). In addition to removing the part of the lung that is affected by the cancer, lung cancer surgeons remove lymph nodes in the chest at the time of lung surgery, to evaluate whether the cancer has spread to these lymph nodes.
Figures 5a-d: Types of Resection
How do I Prepare for Surgery?
Preoperatively, the most important thing that a person can do is to stop smoking if they have not done so already. Smoking before surgery puts people at risk for serious complications (Table 2).
Table 2. Risks of Smoking at the Time of Surgery3, 4
Smoking paralyzes the tiny hairs called cilia that clear secretions out of the airways. Keeping the lungs clean after surgery is an important way to prevent complications after surgery, such as infections and inadequate lung function. Quitting smoking is a simple step that can dramatically improve the chances that surgery will go well, but quitting can be very difficult to do. There are many resources available to help people quit smoking, and the chance of being able to quit successfully is much better if these resources are used.5 Even if a smoker cannot quit long term, they can improve their outcome after surgery if they are able to stop smoking before surgery6 (ideally at least 8 weeks before surgery7 ) and stay off cigarettes until they have successfully healed from surgery.8 See Chapter 11: How to Quit Smoking Confidently and Successfully.
Besides quitting smoking, there are several other things that a person who is anticipating surgery can do to proactively take some control over their surgical course. The patient’s body will be stressed by the surgery, so it is important to prepare as much as possible beforehand. Exercise, proper nutrition, and vitamins (including antioxidants) can help prevent complications from surgery. Even if there are only one or two weeks between the diagnosis and the scheduled date of surgery, every day helps. Making the body as healthy as possible before surgery is a good way to be an active participant in the fight against the cancer.
A daily exercise routine can improve the fitness of the heart and lungs and prepare the body for the stress of surgery. It is important to get approval from your doctor before starting an exercise regimen. Proper nutrition, including a high protein diet, can build up the body’s store of building blocks to use during recovery after the operation.9 Vitamins and antioxidants can be important to help fight off infections and rebuild tissues after surgery.10
What Can I Expect the Day of Surgery?
It is important to arrive at the hospital in plenty of time before the scheduled surgery, to make sure that there is enough time to get ready. After the patient arrives at the hospital, he or she is registered into the hospital system and receives an identifying band to remind all the hospital staff of his or her correct identity, which will be checked repeatedly to make sure that the correct procedures are performed on the correct patient. An intravenous line usually is started for medications. Various tests may be performed, such as blood tests, to make sure that there are no surprises during the course of the operation. Many of the same questions will be asked to recheck the correct information about the patient, such as allergies to medications.
The patient may be asked to stop certain medications before surgery. This is especially important with some blood pressure medications and medications that interfere with blood clotting such as aspirin, warfarin, and clopidogrel. Supplements and naturopathic formulations should be noted on the medication list. Fish oil, omega-3 supplements, Ginkgo biloba, and vitamin E can slow blood clotting and should be discussed with the surgeon. To decrease the possibility of vomiting during anesthesia or sedation, it is important to not eat or drink anything before the procedure. Your doctor will give specific guidelines, but the usual rule is that there should be no food or drink consumed after midnight before surgery. Morning medications usually may be taken with a sip of water.
The patient will meet many new people the day of surgery. There will be an operating room nurse who is in charge of making sure that the operating room works properly. In the operating room, the scrub technologist is in charge of making sure that the surgeon has the equipment he or she needs and keeping the surgical field sterile. The surgeon usually will have an assistant. There will be a doctor or a specialized nurse who will give anesthesia. The anesthetist may talk to the patient about placing an epidural catheter, which is a way of delivering pain medication directly to the fibers in the spinal cord that conduct pain signals to the brain.
The patient will be given an anti-anxiety medication before going to the operating room. In the operating room, the patient will be asked to move onto the operating room bed. This bed is quite narrow, so that the surgeon can easily reach the patient. The patient will be covered in warm blankets because it is important to maintain the body’s usual temperature during the operation to help prevent the patient from getting complications. General anesthesia, in which the patient is completely asleep, is required for most lung operations. After the patient is asleep, the anesthetist places a breathing tube through the mouth into the windpipe. This tube sometimes causes a sore throat after surgery. The patient is positioned on the operating room bed, the skin is scrubbed with an antibacterial scrub, and the patient is covered in sterile drapes. A safety pause is performed to confirm that the correct surgery is being performed on the correct patient and the correct side.
The surgeon makes a skin incision, either a small one for the video camera or a larger incision for open surgery. The tissues of the chest wall are moved out of the way, and an opening is made between the ribs large enough to perform the procedure. After the surgeon can see inside the chest, the first step of the procedure is a careful inspection to make sure that the cancer has not spread further than the preoperative workup indicated and to look for any surprises. If the inspection does not reveal any reason to stop the operation, the surgeon then mobilizes the lung so that it can be moved around more easily into the field of view. Mobilization involves dividing bands of scar tissue and ligaments that hold the lung in place in the chest cavity. After the lung can move freely, the surgeon carefully dissects the lung containing the cancer away from the rest of the body. Specially designed staplers that seal tissue while it is being cut are used to assist with the dissection. The surgeon is always quite careful to not spill cancer into the chest cavity to minimize possibility that the cancer will spread after surgery.
The specimen is removed from the body and given to the pathologist, who carefully cuts the specimen into thin slices, stains the slices, and examines them using a microscope. The pathologist confirms the type of the cancer and assesses how large it is, where it is in relation to the cut edges of the lung and the underlying tissues, and whether lymph nodes are involved. Just like the cancer was staged with imaging and an examination before surgery, the pathologist stages the cancer based on the resected specimen. The staging by the pathologist helps decide whether more therapy (chemotherapy, radiation, or further surgery) is required. The pathologist also tells the surgeon whether the cut edges are free of cancer. If not, more tissue may be taken to get a clean margin. After the cancer has been removed, the surgeon examines the remaining healthy tissues to make sure that all bleeding has stopped, that the remaining lung inflates well, and that no air is leaking out of the remaining healthy lung. After the surgeon is satisfied, he or she usually places a drain to evacuate air and fluid out of the space between the chest wall and the lung (the pleural space). The lung naturally falls away from the chest wall and collapses on itself, but the drain can help hold the lung up against the chest wall. This drain (called chest drain or chest tube) stays in place until the lung is sealed and there is no drainage which is usually 1-3 days after surgery. Finally, the surgeon closes the incision and applies sterile dressings. After the procedure is complete, the patient wakes up in the recovery room. Most people are not aware that any time has passed between when anesthesia was started and when they wake up in the recovery room.
Most people stay in the recovery room for a few hours while the anesthesia wears off. There are nurses in the recovery room who carefully monitor patients to make sure that everything is going well after surgery. A chest radiograph usually is done in the recovery room to recheck that the lung has completely re-expanded after surgery and that the tubes and drains are in the correct locations. After the patient is awake enough to leave the recovery room, he or she is brought to a bed in the hospital to continue recovery.
What Can I Expect During the Hospital Stay?
Being active after surgery can be difficult because chest surgery can be quite painful. However, there are many different ways to control pain after surgery, and the hospital team may select a variety of approaches to deal with the pain from surgery. One of those is placing a small tube, called epidural catheter, alongside the spinal column just outside the membranes that surround the spinal cord. This tube allows a continuous dose of medication to be delivered to the nerves in the spinal cord that transmit pain signals to the brain in order to control the pain. A well placed epidural catheter is one of the most effective ways to control pain after chest surgery.12
Local anesthetics are medications that block the transmission of pain signals along nerve fibers. They may be used in an epidural catheter, or they may be used to directly block the nerves that supply the chest wall, either during or after surgery. Narcotics (also known as opiates) are another class of medications that help control pain after major surgery. They block pain receptors in the brain, spinal cord, and other tissues. Narcotics may be given through an epidural catheter, intravenously (either by a nurse, or with a machine that gives a dose every time a button is pressed), or by mouth. Narcotics can have several unpleasant side effects, such as constipation, confusion, decrease in the drive to breathe, and itching. To limit the amount of narcotics needed to control pain after surgery, many other types of medicines may be used to help control pain. Pain control is important to keep the patient comfortable and allow the patient to move around, cough, and do breathing exercises to prevent complications after surgery.
The entire team in the hospital is focused on preventing the common problems that may occur after surgery. This is the reason that they gather so much data about each patient. Nurses and nurse’s aides check vital signs (including the pain level) several times each day to identify any potential problem early in the course of its development. Radiographs may be taken at several different times during the hospital stay, to make sure that the lung stays fully expanded and that no space develops between the lung and the chest wall. If a chest drain is in place, it is carefully inspected and the amount of fluid coming out of the drain is recorded. Every medication that has been given is documented. All this documentation is focused on making sure that the patient continues to get better all the time, and that any complications that develop are found early.
Despite careful monitoring, complications may occur after surgery. Percentages cited in parentheses are from a large series of lung surgery patients studied at several different hospitals.13 Air leaks are common after lung surgery (8% persist for > 7 days). They happen when the air in the lung leaks into the pleural space (which is the space between the lung and the chest wall). The body is usually able to seal the leak on its own, but large leaks may require repeat surgery.
Heart problems are common after lung surgery because many people with lung cancer have heart
disease, and chest surgery can disturb the heart’s normal rhythm. Irregular heart rhythms such as
atrial fibrillation occur (14%) after surgery, and heart attacks can occur in the postoperative period (< 1%). The body swells and retains fluid in response to injury, and this fluid may take some time to clear after surgery. Infections are a potential complication of any type of surgery. Pneumonia (3%) and infection of the pleural space (1%) are the most common infections after lung surgery. There is a risk of bleeding after any surgery, but the risk of serious bleeding during or after lung surgery is low (2% need blood transfusion, 1% to 2% need reoperation).
Finally, there is a risk that the person with lung cancer cannot function effectively on the amount of lung remaining after the cancer is removed. This is called respiratory failure (5%), and may result in the need for a mechanical ventilator for a short time after surgery, which is a machine that breathes for patients in the Intensive Care Unit (ICU). Some patients with respiratory failure may need portable supplemental oxygen to breathe at home.
What is the Recovery from Lung Cancer Surgery Like?
After lung surgery, lung function usually slowly improves with time, as the remaining lung heals and starts to compensate for the lung that was taken out during surgery. Many people need oxygen for a short time after surgery, and some people are discharged from the hospital with portable oxygen for home use. Oxygen requirements usually decrease with time, and most people that were not on home oxygen before surgery do not require long term oxygen treatment after surgery. The scars also slowly remodel with time and become less noticeable.
The surgeon will want to continue to see the patient in clinic to make sure that the recovery from surgery continues to progress, to answer any questions that may arise, and to put a plan in place for dealing with the cancer in the future. This plan usually involves periodic imaging and checkups to make sure the cancer does not recur. Chemotherapy, radiation, and other treatments may be recommended in addition to surgery according to the final results obtained by the pathologist after analyzing the cancer, the lung and the lymph nodes resected during the surgery. This determines the final stage of the cancer more accurately than the preoperative tests.
Am I Cured?
With modern surgery, possibly accompanied by chemotherapy and radiation, it is common for people with early stage lung cancer to be completely cured (Table 3).
Table 3. Five-Year Survival
|Stage I||Stage IIA||Stage IIB||Stage IIIA||Stage IIIB||Stage IV|
Table 3. The Percentage of Patients with Non-small Cell Lung Cancer who are Alive Five Years After Diagnosis14, 15
For physicians, cure or survival is measured at the five-year mark. Although many people may return to their normal lives after surgery, people often wonder if the cancer will return. The longer people live after completing their treatment, the smaller risk they have of having the cancer recur. Five years after treatment is completed, we consider a patient to be cured, and we celebrate this landmark with all of our patients who reach it. However, during these 5 years, it’s important to follow a surveillance program in order to detect early cancer recurrence or a new lung cancer. This program that is generally proposed by the surgeon and consists in both periodical physical examination and imaging tests, should be completed by the patient.
Lung cancer is a frightening diagnosis, but treatments have markedly improved in recent years. Surgery to remove the lung that contains the cancer is the mainstay of treatment in early stage non-small cell lung cancer. Successful surgery is a partnership between the surgeon and the patient. The surgeon will thoroughly evaluate the patient with lung cancer to determine if surgery is the best option. The patient should actively participate in his or her care by stopping smoking, remaining active or becoming more active, and eating a healthy diet. The patient and the surgeon need to work together to make sure that the surgical and non-surgical care of lung cancer give the best potential for long term cure of the cancer and a quick return to normal life.
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