Lung Cancer News Update

Lung Cancer Vaccine Could Lead to Mesothelioma Vaccine “The groundbreaking development of a lung cancer vaccine could change everything about lung cancer treatment – and even mesothelioma treatment. A lung cancer immunotherapy drug, CIMAvax-EGF, has made steady strides in the treatment of lung cancer. Due to the drug’s success, a team of researchers at Roswell Park Comprehensive Cancer Center is applying the immunotherapy drug in revolutionary ways.” CAR-T cell therapies eliminate residual, drug-resistant lung cancer cells in preclinical tests “Targeting a cell surface protein could eliminate the lung cancer cells that survive treatment with epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs), according to a paper published on Monday in Cancer Cell.” Early-life exposure to tobacco raises risk for lung cancer, mortality in adulthood “Being exposed to tobacco in utero and in childhood/adolescence was linked to higher risks for lung cancer incidence and death later in life, according to study results published in American Journal of Respiratory and Critical Care Medicine.” Neoadjuvant Nivolumab Shows Long-term Benefit in Patients with Non-small Cell Lung Cancer “PHILADELPHIA – Patients with resectable non-small cell lung cancer (NSCLC) who were treated with neoadjuvant nivolumab had improved five-year recurrence-free and overall survival rates compared with historical outcomes, according to results published in Clinical Cancer Research, a journal of the American Association for Cancer Research (AACR).” Cornell Scientists Uncover Major Mechanism Behind Lung Cancer’s Immune Evasion “According to a study led by researchers at Weill Cornell Medicine, a protein prevalent in high quantities within lung cancer cells has been found to regulate a critical immunosuppressive pathway, enabling lung tumors to avoid immune response. This discovery could accelerate the creation of treatments aimed at overcoming this tumor defense mechanism, ultimately enhancing the prospects for lung cancer patients.” Video: Video game-like controller helps Reston surgeons detect lung cancer in patients “FAIRFAX COUNTY, Va. (7News) — A new surgical robot at Reston Hospital Center is helping doctors find and diagnose lung cancer in patients through minimally invasive procedures. It’s surgery without any external incisions.” Traveling Through the Lung Cancer Treatment Paradigm: Biomarker Guidance in NSCLC “In this second episode of OncChats: Traveling Through the Lung Cancer Treatment Paradigm, Aaron Franke, MD, discusses the need for additional circulating biomarkers beyond PD-L1 in non–small cell lung cancer.”