Weekly News
Weekly news updates are currently posted on our homepages, weekly news pages and sent directly to your inbox to provide up-to-date information on what has been covered in the news regarding lung cancer, and complementary health & wellness in the previous week.
Lung Cancer News Update
by Lorren Sandt | March 18, 2024 | Weekly News | 0 Comments
Nearly half of patients with positive lung cancer screening findings delay follow-up care
“Key takeaways: Delaying follow-up after receipt of positive lung cancer screening findings was relatively common. Patients with lung cancer had a high likelihood of clinical upstaging if they delayed follow-up.”
Lung Cancer Survivors and Caregivers Take Their Stories to Capitol Hill to Advocate for Lifesaving Research and Public Health Funding
“WASHINGTON, March 18, 2024 /PRNewswire/ — On Wednesday, March 20, LUNG FORCE Heroes—people living with lung cancer, their loved ones and advocates from across the country—will travel to Washington, D.C. to advocate for lifesaving research and public health funding. As a part of the American Lung Association LUNG FORCE Advocacy Day, the advocates will meet with members of Congress to share their stories, and ask them to support $51.3 billion in research funding for the National Institutes of Health (NIH) and $11.6 billion in funding for the Centers for Disease Control and Prevention (CDC).”
GRAIL Announces Novel Risk Classification Test to Be Used in Lung Cancer Study
“MENLO PARK, Calif. & CAMBRIDGE, England–(BUSINESS WIRE)– GRAIL, LLC, a healthcare company whose mission is to detect cancer early when it can be cured, announced today that participants from Japan, via a collaboration with AstraZeneca (LSE/STO/Nasdaq:AZN), will have their samples tested using GRAIL’s novel risk classification test on its Methylation Platform. This assay has been validated for recurrence risk classification in newly diagnosed Stage I lung adenocarcinoma.”
Early Onset of Lung Cancer in Small Areas as a Signature of Point Pollution Sources
“At a small-area scale, the detrimental effect of air pollution on lung cancer is challenging to identify and measure due to the potentially scattered detection of pollutants and/or limited statistical power of available indicators. A novel method is presented to detect and quantify the detrimental impact of pollution in small areas by employing the early onset of lung cancer as a signature of pollution. Early-onset lung cancer may speed up the investigation of potential environmental hazards in a specific area, enabling public health officials or citizen committees to carry out geographical analyses.”
FDA Accepts NDA for Ensartinib in Metastatic ALK-Positive NSCLC
“The regulatory agency set an action date of December 28, 2024 for ensartinib as a treatment for those with ALK-positive non–small cell lung cancer.”
Study Reveals New Insights Into Immune System Role in Lung Cancer Risk
“Recent developments in cancer research have highlighted the vital role of the immune system, particularly in the notable successes of cancer immunotherapy. Now, a paradigm-shifting study led by researchers at the Icahn School of Medicine at Mount Sinai in New York in collaboration with the University of Helsinki, Massachusetts General Hospital, and the Broad Institute of MIT and Harvard sheds light on how variations in immune genetics influence lung cancer risk, potentially paving the way for enhanced prevention strategies and screening.”
Lung Cancer Replaces Breast Cancer as Most Common Form Among Chinese Women
“(Yicai) March 14 — Lung cancer has surpassed breast cancer as the most frequent type of malignant tumor among Chinese women amid the aging population. In 2022, China had 402,000 women with lung cancer and 357,000 people with breast cancer, according to the most recent report by the National Cancer Center. The nation recorded almost 1.1 million new lung cancers, making up 22 percent of all new cases of diseases linked to abnormal cell growth.”
Immunotherapy Trials for Metastatic NSCLC: FDA Pooled Analysis
“In a U.S. Food and Drug Administration (FDA) pooled analysis reported in The Lancet Oncology, Bernardo Haddock Lobo Goulart, MD, and colleagues found that response rate and progression-free survival were only moderately correlated with overall survival in first-line immunotherapy trials for metastatic non–small cell lung cancer (NSCLC).”
My Choices News Update
by Lorren Sandt | March 12, 2024 | Weekly News | 0 Comments
Oregon needs to listen to its patients
“More than half of Oregonians are living with at least one chronic health condition. One in four adults has a disability, and around 20,000 people receive a cancer diagnosis each year. Right now, our state is making critical drug pricing decisions that could make it harder for these patients to access the care they need. And it’s doing so without even giving them a seat at the table.”
Grant to Support Liver Disease Drug Development, Potentially Reduce Animal Testing
“Liver disease researchers at the University of Pittsburgh School of Medicine (UPSM) will use a $7.8 million federal grant to build a new drug discovery center, which will test whether using human cells can replace animals in determining if and how a new drug works.”
Complementary Health Approaches for Pain Management Increasing in Popularity
“Complementary health approaches, like yoga or acupuncture, can be particularly appealing to patients seeking natural and non-invasive approaches to improve their health.”
Guidance on Use of Race, Ethnicity, and Geographic Origin as Proxies for Genetic Ancestry Groups in Biomedical Publications
“In March 2023, the National Academies of Sciences, Engineering, and Medicine (NASEM) released a consensus study report titled Using Population Descriptors in Genetics and Genomics Research.1 Sponsored by the US National Institutes of Health, the report is more than a discussion of the use of terminology; the authors of the NASEM report suggest a tectonic shift away from current models that use race, ethnicity, and geographic origin as proxies for genetic ancestry groups (ie, a set of individuals who share more similar genetic ancestries) in genetic and genomic science.”
Why Diet Matters for the Planet and Your Health
““The hottest year was even hotter than expected,” read a recent headline in Science. If, like me, you want to do more to stave off the worst, then cast a more critical eye on diet. What we eat has a major climate impact, because food production generates high levels of the greenhouse gases (GHG) that underlie climate change.”
Navigating nutrition facts and fads
“In a world of diet trends and conflicting nutrition information, it can feel like you are bombarded by tons of “solutions” for health improvement every day. The truth is there is no one size fits all approach when it comes to personal nutrition. Jaime Gnau, clinical assistant professor in the public health and sports medicine department at Missouri State University, brings over 20 years of health care experience to her role.”
Habitual Short Sleep Duration, Diet, and Development of Type 2 Diabetes in Adults
“Question Is there an association between adherence to healthy diet, sleep duration, and risk of developing type 2 diabetes (T2D) in adults?
Findings This cohort study analyzing data from 247 867 adults in the UK Biobank found that individuals sleeping less than 6 hours daily had a notably higher risk of developing T2D compared with those with 7 to 8 hours of sleep. Despite the association between healthier diets and reduced T2D risk, the increased risk associated with short sleep duration persisted even among adults with healthy eating habits.
Meaning These findings suggest that adopting a healthy diet may not reduce the risk of developing T2D among those with habitual short sleep duration.”
Women who do strength training live longer. How much is enough?
“Resistance training does more than help us build strong muscles. A new study finds women who do strength training exercises two to three days a week are more likely to live longer and have a lower risk of death from heart disease, compared to women who do none.”
Walking 5,000 Steps Three Times Per Week Could Add Three Years to Life Expectancy
“LONDON, March 12, 2024–(BUSINESS WIRE)–New research published by Vitality and the London School of Economics shows that sustaining a healthy exercise habit of at least 5,000 steps three times per week for two years can add up to three years to an individual’s life expectancy and reduce their healthcare costs by up to 13%.”
Demographic, health, physical activity, and workplace factors are associated with lower healthy working life expectancy and life expectancy at age 50
“This study identified demographic, health, physical activity, and workplace factors associated with lower HWLE and life expectancy at age 50. Identifying the extent of the impact on healthy working life highlights these factors as targets and the potential to mitigate against premature work exit is encouraging to policy-makers seeking to extend working life as well as people with musculoskeletal and mental health conditions and their employers. The HWLE gaps suggest that interventions are needed to promote the health, wellbeing and work outcomes of subpopulations with long-term health conditions.”
Lung Cancer News Update
by Lorren Sandt | March 11, 2024 | Weekly News | 0 Comments
Non-smoking Asian women have higher rates of lung cancer than other non-smokers
“Lung cancer rates are in decline across almost group, except non-smoking Asian American women, whose rates are increasing by 2% every year, a California study found. While 20% of all lung cancer cases are found in non-smokers, the study found that of Asian American women who have lung cancer, over 50% of that group are nonsmokers, according NBC News.”
Evolving Strategies in Managing and Treating Small Cell Lung Cancer
“Ariel Lopez-Chavez, MD, provided insights into the current landscape of small cell lung cancer treatment, highlighting approved options and ongoing research.”
The Young Ambassador for Women With Lung Cancer
“Diagnosed with Stage IV lung cancer at age 33, Sydney Barned, MD, a nonsmoker, is on a mission to get this disease the attention it deserves, including among young women.”
VA announces steps to increase life-saving screening, access to benefits for Veterans with cancer
“WASHINGTON —Today, as a part of the Biden Cancer Moonshot, VA announced several critical new steps to expand preventive services, health care, and benefits for Veterans with cancer”
Hope and Innovation in the Lung Cancer Space
“Lung cancer, the leading cause of cancer-related mortality worldwide, poses significant challenges to patients, caregivers and health care professionals alike. This special issue of CURE provides information on recent treatment developments, as well as insight into some of the issues currently faced by patients.”
Lung cancer disproportionately affecting Black communities
“New data reveals a harsh reality for Black and African Americans diagnosed with lung cancer, shedding light on disparities in early detection and access to care. Corey James investigates this pressing issue and speaks with Dr. Jonathan Villena, a thoracic surgeon specializing in lung cancer treatment at Weill Cornell Medicine and New York Presbyterian Hospital, for insights.”
Research Reveals Cigarette Smoke Shield for Lung Cancer Cells
“UNIVERSITY PARK, Pa. — Lung cancer cells survive better and exhibit less cell damage when exposed to cigarette smoke in cell culture experiments compared to non-cancerous lung cells. New research by a team of undergraduate students led by a Penn State molecular biologist may have revealed how lung cancer cells can persist in smoke. The mechanism could be related to how cancer cells develop resistance to pharmaceutical treatments as well.”
Lung cancer treatment shows promise in tumor models
“DALLAS – March 11, 2024 – A molecule has demonstrated its ability to kill tumor cells and incite an immune response in preclinical models of small cell lung cancer (SCLC), according to UT Southwestern Medical Center researchers. The findings, published in Nature Communications, could lead to more successful treatments for SCLC, one of the leading causes of cancer-related deaths in the U.S.”
AI may predict spread of lung cancer to brain
“Scientists at Washington University School of Medicine in St. Louis trained a machine-learning algorithm to predict accurately brain metastasis using biopsy samples from early-stage non-small cell lung cancer patients. It was also highly accurate in predicting those patients who do not develop metastatic brain tumors.”
My Choices News Update
by Lorren Sandt | March 4, 2024 | Weekly News | 0 Comments
Revolutionary Study Unveils Exercise as a Key to Unlocking Better Sleep for All Ages
“In the hustle of our daily lives, where the glow of screens often replaces the setting sun, a groundbreaking study from the University of South Australia offers a beacon of hope. It suggests a simple yet profound solution to the widespread struggle for a good night’s sleep: more physical activity. Involving 1,168 children and 1,360 adults, primarily mothers, the research illuminates the profound impact of daily exercise on sleep quality, challenging the conventional wisdom that focuses on pre-bedtime rituals.”
Determinants and outcomes of health-promoting lifestyle among people with schizophrenia
“Healthy lifestyle is an important protective factor of developing cardiovascular disease in people with schizophrenia. However, little is known about the determinants of lifestyle and its contribution to metabolic syndrome. This study aimed to explore the influencing factors of health-promoting lifestyle (HPL) and its association with metabolic syndrome among people with schizophrenia.”
One in eight people are now living with obesity
“Geneva, March 1, 2024 — New study released by the Lancet shows that, in 2022, more than 1 billion people in the world are now living with obesity. Worldwide, obesity among adults has more than doubled since 1990, and has quadrupled among children and adolescents (5 to 19 years of age). The data also show that 43% of adults were overweight in 2022.”
Belly fat linked to cognitive decline in people at risk for Alzheimer’s
“Researchers from Rutgers University say abdominal fat could impact brain health and cognition among people at risk for Alzheimer’s disease. Researchers found that middle-aged males with a high Alzheimer’s risk who had higher amounts of pancreatic fat had lower cognition and brain volumes. Abdominal fat also affected Alzheimer’s risk among female participants, but less so compared to males.”
Researchers unveil innovative remote nutrition education for adolescents with intellectual disability
“Researchers have unveiled innovative strategies to promote healthy eating habits among adolescents with special needs. MaryAnn Demchak, Ph.D., BCBA-D., professor of special education at the University of Nevada, Reno and alumna Brianna Grumstrup, Ph.D., assistant professor of special education at the University of Maine, Farmington, conducted a study utilizing the System of Least Prompts (SLP) delivered remotely to provide nutrition education to high school students with an intellectual disability.”
Study reveals broader elements of personal recovery for individuals at risk of mental illness
“Definitions of what recovery means to people at risk of mental illness should extend beyond symptom remission into broader areas of life and wellbeing. According to researchers at the University of Birmingham, ‘personal recovery’ – defined as a person’s capacity to live a full meaningful life in a community of one’s choosing despite the limitations imposed by illness – can be experienced by people at risk of developing serious mental health problems.”
Yogurts can now make limited claim that they lower type 2 diabetes risk, FDA says
“In a decision nearly five years in the making, the US Food and Drug Administration has decided that yogurts can now make a limited claim that the food may reduce the risk of type 2 diabetes, the federal agency concluded Friday. The decision marks the first-ever qualified health claim the federal agency has issued for yogurt.” BUT read more…
Living near pubs, bars and fast-food restaurants could be bad for heart health
“Closer proximity to and a higher number of ready-to-eat food outlets — particularly pubs, bars and fast-food restaurants — may be associated with a greater risk of developing heart failure, according to a study of half a million adults in the UK Biobank. The association between food environments and increased heart failure risk was stronger among people who did not have a college degree and those living in urban areas without access to facilities for physical activity such as gyms or fitness centers.”
Mindful Eating Aims to Change Your Relationship With Food
“March 1, 2024 – You may be familiar with the basic steps: Slow down, notice what you’re eating, and enjoy your food. But mindful eating can be more nuanced, and if done with intention over time, it can change your relationship with food and benefit your health, experts say.”
Floating Towards Wellness: The Rising Tide of Sensory Deprivation Tanks in Stress Reduction and Therapy
“In an era where the quest for tranquility often leads to crowded yoga classes and mindfulness apps, a seemingly unconventional method is making waves in the health and wellness industry. Sensory deprivation tanks, also known as float tanks, are offering individuals a unique escape into stillness and serenity. By minimizing external sensory input, these tanks are not just about floating; they’re about fostering a profound sense of peace and well-being.”
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1 in 3 women are impacted by obesity, but treatments are often uncovered
“NEW YORK — One in three women are impacted by obesity, according to the Kaiser Family Foundation. The disease is associated with more than 200 different health conditions, but treatments are often not covered by insurance. The Alliance for Women’s Health and Prevention is advocating for change with a new campaign.”
Lung Cancer News Update
by Lorren Sandt | March 4, 2024 | Weekly News | 0 Comments
Study highlights disparities in lung cancer treatment access across Europe
“There are stark differences between European countries when it comes to both the reimbursement of, and access to, new treatments for patients with early-stage lung cancer. There are also differences in reimbursement times and indications between the European Medicines Agency (EMA) and the US Food and Drug Administration (FDA).”
J&J (JNJ) Secures Full FDA Nod for Rybrevant in Lung Cancer
“Johnson & Johnson (JNJ Quick QuoteJNJ – Free Report) announced that the FDA granted full approval to its EFGR/MET inhibitor Rybrevant (amivantamab) in non-small cell lung cancer (NSCLC) indication. Following the FDA decision, Rybrevant, in combination with chemotherapy (carboplatin-pemetrexed), is approved for the first-line treatment of patients with locally advanced or metastatic NSCLC with EGFR exon 20 insertion mutations.”
FDA lifts clinical hold on Iovance lung cancer trial
“SAN CARLOS, Calif. – Iovance Biotherapeutics, Inc. (NASDAQ:IOVA), a biotechnology company specializing in novel cancer therapies, announced today that the U.S. Food and Drug Administration (FDA) has removed the partial clinical hold on the IOV-LUN-202 trial. This pivotal study is assessing the efficacy of LN-145, a tumor infiltrating lymphocyte (TIL) cell therapy, in treating non-small cell lung cancer (NSCLC).”
Microbial signatures linked to immunotherapy response across cancers
“The microbiome can identify those who benefit from combination immunotherapy across multiple different cancers, including rare gynecological cancers, biliary tract cancers and melanoma. Researchers from the Wellcome Sanger Institute, the Olivia Newton-John Cancer Research Institute in Australia, and collaborators, have identified specific strains of bacteria that are linked with a positive response to combination immunotherapy in the largest study of its kind.”
Large-scale study explores link between smoking and DNA changes across six racial and ethnic groups
“Smoking changes the way genes are expressed, which later contributes to the development of lung cancer and other smoking-related illnesses. But the link between epigenetics (the study of mechanisms that impact gene expression) and smoking is not fully understood, especially in terms of differences across racial and ethnic groups.”
Lung Cancer in Women—Sociodemographic, Clinical and Psychological Characteristics with Comparison to Men
“Background: There is a difference in the course of lung cancer between women and men. Therefore, there is a need to evaluate various factors in the patient population treated in daily practice. The purpose of this study was to analyze the clinical, sociodemographic and psychological aspects of female lung cancer. To better express the results, we compared women and men.”
Evaluating the Feasibility of Lung Cancer Screening in High-risk Black Women CLINICAL TRIAL / NCT05898594
“The goal of this research study is to study U.S. Black women with a history of smoking to examine the feasibility, acceptability, and performance of low-dose computed tomography (LDCT) screening among this population. The name of the intervention used in this research study is: Low-dose computed tomography (radiologic scan) chest scan”
Creo device used in ‘groundbreaking’ lung cancer procedure
“Creo Medical Group announced a significant milestone in the field of minimally-invasive surgical endoscopy for cancer patients on Friday, with its ‘MicroBlate Flex’ device. The AIM-traded company announced that professor Pallav Shah and Dr Christopher Orton, specialists from the Royal Brompton Hospital, had successfully conducted the world’s first robotic-guided microwave ablation of lung tissue concurrently with a diagnostic procedure.”
Doctors Say These 4 Potential Signs Of Lung Cancer Are Something Everyone Should Know About
“According to the American Cancer Society, lung cancer is the leading cause of cancer death in the United States, accounting for 1 out of every 5 cancer fatalities. Early detection is imperative for increasing survival with lung cancer before the disease spreads beyond the lungs.”
Groundbreaking Atlas by MD Anderson Unveils New Pathways in Lung Cancer Detection and Treatment
“In the ongoing battle against lung cancer, a formidable enemy with a stealthy approach and devastating impact, a new weapon has been forged in the laboratories of The University of Texas MD Anderson Cancer Center. This cutting-edge tool, a comprehensive atlas of lung cells, promises to revolutionize our understanding and treatment of lung adenocarcinoma, the most common guise in which lung cancer presents itself.”
Nuvalent Granted FDA Breakthrough Therapy Designation for Non–Small Cell Lung Cancer Drug
“Nuvalent, Inc’s novel, brain-penetrant, ROS1-selective tyrosine kinase inhibitor (TKI) NVL-520 has been granted Breakthrough Therapy Designation by the FDA to treat patients with metastatic ROS1-positive non–small cell lung cancer (NSCLC) who received prior therapy with at least two ROS1 TKIs.”
Clinical Value of Timely Targeted Therapy for Patients With Advanced Non–Small Cell Lung Cancer With Actionable Driver Oncogenes
“A recent real-world study observed that 24% of patients with advanced non–small cell lung cancer (aNSCLC) with actionable driver oncogenes (ADOs) initiated nontargeted therapies before biomarker test results became available. This study assessed the clinical impact of the timing of first-line (1L) targeted therapies (TTs) in aNSCLC.”
FDA Awards Breakthrough Therapy Designation to Novel HER2-Activating NSCLC Therapy
“The FDA has granted a breakthrough therapy designation to BAY 2927088, an oral, small molecule tyrosine kinase inhibitor (TKI) for patients with non-small cell lung cancer (NSCLC) harboring HER2-activating mutations. Breakthrough therapy designation is intended to expedite the development and review of drugs that treat serious conditions and show improvement over currently available therapies. This designation marks a new potential treatment for the most common type of lung cancer.”
NCCN Updates Treatment Recommendations for Breast, Colorectal, Lung, and other Cancer Types Based on Emerging Evidence
“PLYMOUTH MEETING, Pa., March 4, 2024 /PRNewswire/ — The National Comprehensive Cancer Network® (NCCN®) is announcing several new updates to the cancer treatment practices listed in the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®). The evidence-based expert consensus recommendations are the most frequently updated guidelines for any area of medicine and are used by cancer care providers worldwide to stay up to date on innovations. Recently, the alliance of leading cancer centers published updated versions for several high-incidence cancer types, including breast, colorectal, lung, and pancreatic.”
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Expert Discusses Radiotherapy Recommendations for SCLC Management
“Prophylactic cranial irradiation may not be worthwhile for treating patients with extensive-stage small cell lung cancer based on conflicting data, according to Gregory Peter Kalemkerian, MD.”
My Choices News Update
by Lorren Sandt | February 26, 2024 | Weekly News | 0 Comments
Understanding and Reducing Your Cancer Risk: Insights from Dr. Jon Ebbert
“February marks National Cancer Prevention Month, a time when we turn our collective focus towards the prevention strategies that can help us reduce the risk of cancer. A leading voice in this discussion is Dr. Jon Ebbert, the medical director of the Mayo Clinic Nicotine Dependence Center. Dr. Ebbert’s extensive research and expertise shed light on the significant role that lifestyle choices, including tobacco use, alcohol consumption, and maintaining a healthy weight, play in influencing cancer risk.”
A quarter of smokers quit within a year or two of menthol bans, researchers find
“Menthol cigarette bans are effective at getting people to quit smoking, new research finds. The U.S. Food and Drug Administration has said that a menthol ban is a “top priority,” but public health advocates have accused the Biden administration of dragging its feet, and the ban has gotten caught up in election-year politics despite research showing clear health benefits.”
Is Housing Health Care? State Medicaid Programs Increasingly Say ‘Yes’
“States are plowing billions of dollars into a high-stakes health care experiment that’s exploding around the country: using scarce public health insurance money to provide housing for the poorest and sickest Americans.”
The Atlantic Diet: Why Eating Local, Whole Foods May Improve Your Health
“This trendy diet may help stave off chronic disease, but it’s one of many eating patterns that prioritize whole foods and richness.”
Physical activity improves stress load, recovery, and academic performance-related parameters among university students: a longitudinal study on daily level
“Physical activity has been proven to be beneficial for physical and psychological health as well as for academic achievement. However, especially university students are insufficiently physically active because of difficulties in time management regarding study, work, and social demands. As they are at a crucial life stage, it is of interest how physical activity affects university students’ stress load and recovery as well as their academic performance.”
Sleep, Exercise, and Avoiding Cigarettes are Key to Reducing IBS Risk
“Adopting healthy lifestyle habits is linked to a decreased risk of irritable bowel syndrome (IBS). These habits include not smoking, vigorous physical activity, and getting enough quality sleep. Experts said that not smoking may reduce inflammation, exercise can regulate bowel movements and sleep can boost immune function – all of which contribute to a healthy gut and minimizing IBS symptoms. To treat IBS, avoid spicy foods, caffeine, and alcohol. Also, exercise regularly, don’t smoke and practice good sleep hygiene.”
Mindfulness at work protects against stress and burnout
“A new study has revealed that employees who are more mindful in the digital workplace are better protected against stress, anxiety and overload. Researchers from the University of Nottingham’s Schools of Psychology and Medicine analysed survey data from 142 employees. The results have been published today in PLOS ONE.”
Lung Cancer News Update
by Lorren Sandt | February 26, 2024 | Weekly News | 0 Comments
How thawing Arctic permafrost could cause lung cancer
“Among the cataclysmic effects of global warming, not many of us have considered a potential rise in cancer cases. And yet, thawing permafrost in the Arctic could provoke just that. The layer, which keeps the ground frozen in the polar region all year round, traps in a variety of gases, preventing them from being emitted into the atmosphere.”
Innovative ‘Trojan Horse’ Method Developed to Target Lung Cancer More Effectively
“Researchers have developed a groundbreaking ‘Trojan horse’ approach to target lung cancer cells with precision. This innovative method shows promise in reducing tumor size and improving patient outcomes. Despite challenges, this approach offers hope in the fight against lung cancer.”
City of Hope launches life-saving mobile cancer unit that brings screenings to your doorstep
“LOS ANGELES (KABC) — Getting regular screenings are key to catching cancer early, but many people put off going to the doctor. Now, City of Hope is launching its first mobile cancer screening unit with the aim of saving lives. It’s as big as those giant trucks you see on the highway, but inside, there’s life-saving cargo designed to deliver leading-edge cancer screening right to your doorstep.”
Pharmacy Focus: Oncology Edition- Latest Updates in Non-Small Cell Lung Cancer Treatment
“ Key Takeaways
Pharmacists play an important role in chemotherapy management for NSCLC patients, but insurance coverage can be a barrier.
Osimertinib in combination with chemotherapy received FDA approval for locally advanced or metastatic EGFR-mutated NSCLC and showed improved progression-free survival.
Datopotamab deruxtecan received FDA approval for previously treated locally advanced or metastatic non-squamous NSCLC.
A phase 3 trial of sacituzumab govitecan failed to meet its primary endpoint of improved overall survival in metastatic NSCLC, though some benefit was seen in squamous and non-squamous subgroups.”
Guiding Lung Cancer Treatment During Pregnancy
“Lung cancer is on the rise in young people, particularly those who are assigned female at birth (AFAB). As a result, there is an increase in the number of people who are pregnant and have lung cancer. Florez has become known for her care of pregnant lung cancer patients and has begun a quest to determine the best approach to their treatment.”
Rural ground wells increase risk of higher radon levels, study finds
“’The air around the groundwater well itself is acting as a sort of superhighway,’ Calgary study author says”
A dynamic nomogram predicting symptomatic pneumonia in patients with lung cancer receiving thoracic radiation
“The most common and potentially fatal side effect of thoracic radiation therapy is radiation pneumonitis (RP). Due to the lack of effective treatments, predicting radiation pneumonitis is crucial. This study aimed to develop a dynamic nomogram to accurately predict symptomatic pneumonitis (RP ≥ 2) following thoracic radiotherapy for lung cancer patients.”
How chronic stress spreads cancer
“Stress is inevitable. But too much of it can be terrible for our health. Chronic stress can increase our risk for heart disease and strokes. It may also help cancer spread. How this works has remained a mystery—a challenge for cancer care.”
My Choices News Update
by Lorren Sandt | February 20, 2024 | Weekly News | 0 Comments
Redefining Cancer: A New Approach to Early Stage Diseases
“The understanding of disease biology for many cancer types has significantly advanced in recent years. However, this progress is not always mirrored in the way cancer is defined and treated. This can lead to overdiagnosis and overtreatment, particularly in cancers such as ductal carcinoma in situ (DCIS) and low-grade prostate cancer, which pose minimal risks for mortality or diminished quality of life.”
Scientists Tame Shapeless Monster Behind 75% of Cancers
“Researchers at UC Riverside have made a groundbreaking discovery in cancer treatment by developing a peptide that can control MYC, a key protein involved in the majority of human cancers. This innovation offers new hope for targeting cancer at a molecular level, paving the way for more effective treatments.”
Revolutionizing Recovery: Ottawa Study Unveils VR Mindfulness as a Beacon for Veterans
“In Ottawa, a revolutionary study by the University of Ottawa uncovers the transformative potential of VR mindfulness training for veterans grappling with substance use recovery. This immersive approach enhances mood, state mindfulness, and overall well-being, shedding light on promising therapeutic interventions for mental health.”
Tai chi reduces blood pressure better than aerobic exercise, study finds
“Tai chi, a traditional, slow-moving form of Chinese martial art, is known to increase flexibility and improve balance. Now, new research suggests it’s better than more vigorous aerobic exercises for lowering blood pressure in people with prehypertension.”
How Exercise Can Help Boost Your Memory
“Forgetting information. Losing focus. Having difficulty doing tasks you used to find easy, like following a recipe or running errands. Struggling to remember the word for that thing…”
Exercise unleashes anti-inflammatory power against autoimmune diseases
“In a recent study published in Journal of Sport and Health Science, a group of researchers evaluated the impact of exercise training on reducing inflammation in adolescents and adults with autoimmune diseases through a systematic review of studies published over two decades.”
Women may get more health benefits from regular exercise than men
“Men and women who exercise regularly are less likely to die prematurely of any cause, including a cardiovascular event, compared to those who are sedentary. Researchers also report that women see more pronounced benefits than men from regular exercise. They added that exercise routines should contain both aerobic exercise and strength training.”
How To Get Sculpted Arms Like Miley Cyrus
“Do you feel like your arms could do with a serious tune-up but can’t afford a personal trainer or gym fees? We share a celebrity-inspired workout you can carry out at home without the celebrity price tag.”
Monday Medical: How integrative medicine can improve your health
“The more physicians and patients explore the many ways integrative medicine can be used to promote health and healing, the more it has become an integral component of American health care. “Both physicians and patients just need to have an open mind,” said Dr. Nicole Cotter, a board-certified rheumatologist and integrative medicine physician at UCHealth Yampa Valley Medical Center. “Every patient can benefit from integrative medicine, and every physician can benefit from introducing elements of it into treating patients. In fact, primary care physicians are probably doing it more than their patients realize. Many people aren’t familiar with the name ‘integrative medicine,’ even though they are likely using it in one form or another.” Surveys show that 40% of Americans participate in some type of integrative medicine. It combines traditional or conventional medical practices with complementary medicine modalities, so patients receive the best of both approaches.”
Lung Cancer News Update
by Lorren Sandt | February 20, 2024 | Weekly News | 0 Comments
Tagrisso with the addition of chemotherapy approved in the US for patients with EGFR-mutated advanced lung cancer
“AstraZeneca’s has been approved in the US for the treatment of adult patients with locally advanced or metastatic epidermal growth factor receptor-mutated (EGFRm) non-small cell lung cancer (NSCLC). The approval following a Priority Review by the Food and Drug Administration (FDA) was based on the results from the FLAURA2 Phase III trial published in The New England Journal of Medicine. Tagrisso with the addition of chemotherapy reduced the risk of disease progression or death by 38% compared to Tagrisso monotherapy which is the 1st-line global standard of care (hazard ratio [HR] 0.62; 95% confidence interval [CI] 0.49-0.79; p<0.0001). Median progression-free survival (PFS) by investigator assessment was 25.5 months for patients treated with Tagrisso plus chemotherapy, an 8.8-month improvement versus Tagrisso monotherapy (16.7 months).”
Risk-based lung cancer screening in heavy smokers: a benefit–harm and cost-effectiveness modeling study
“Risk-based screening strategies are more efficient in reducing lung cancer deaths and gaining life years compared to the status quo strategy. Risk-stratified screening intervals can potentially balance long-term benefit–harm trade-offs and improve the cost-effectiveness of lung cancer screenings.”
FDA Accepts Dato-DXd Application for Non-Small Cell Lung Cancer
“The BLA for Dato-DXd, a TROP2-directed ADC, in previously treated, advanced, nonsquamous NSCLC has been accepted by the FDA, and a PDUFA target action date is anticipated in the fourth quarter of 2024.”
Reflex Molecular Testing May Enhance Targeted Therapy Benefit in Early-Stage Lung Cancer
“Efforts to standardize and implement reflex testing for biomarkers in early-stage non–small cell lung cancer could allow for earlier identification of appropriate targeted therapies that may be used in treatment, thereby improving patient outcomes, according to Jobelle Baldonado, MD, who adds that it is important for surgical oncologists to stay up to date on the development of targeted agents in lung cancer so they can best treat patients presenting with recurrent disease.”
Work-Related Respirable Crystalline Silica Exposure and Lung Cancer Risk
“Prevention measures should be taken to protect workers who are exposed to respirable crystalline silica (RCS) from lung cancer risk. Researchers assessed a systemic review of 20 studies found using the PubMed database and an online search of RCS limits set by institutional organizations. They sought to determine the cutoff points that could affect risk of mortality or incidence of lung cancer from occupational RCS exposure.”
Osimertinib Yields Activity, Manageable Toxicity in Metastatic EGFR+ NSCLC
“Treatment with osimertinib (Tagrisso) demonstrated clinical activity and a manageable safety profile among patients with metastatic non–small cell lung cancer (NSCLC) harboring EGFR mutations outside of exon 20 insertion mutations, according to findings from the phase 2 UNICORN trial (jRCTs071200002) published in JAMA Oncology.”
‘Help is right here’: Roswell Park brings lung cancer screening to people who need it
“Eddy is Roswell Park Comprehensive Cancer Center’s new mobile lung cancer screening unit – the size of a tractor-trailer – and its mission is in its name: “Early Detection Driven to You.”
Kentucky rises to No. 2 in the nation in screening for lung cancer, which lowers the chances that the disease will be fatal
“Dr. Tony Stumbo’s heart sank after the doctor shared his mother’s chest X-ray. “I remember that drive home, bringing her back home, and we basically cried,” said the internal medicine physician, who had started practicing in Eastern Kentucky near his childhood home in Floyd County shortly before his mother began feeling ill. “Nobody wants to get told they’ve got inoperable lung cancer. I cried because I knew what this meant for her.” Now Stumbo, whose mother died the following year, in 1997, is among a group of Kentucky clinicians and researchers determined to rewrite the script for other families by promoting training and boosting awareness about early detection in the state with the highest lung cancer death rate.”
Study Finds New Inhalable Therapy is a Big Step Forward in Lung Cancer Research
“Newswise — Lung cancer is one of the most common cancers and has one of the lowest survival rates in the world. Cytokines, which are small signaling proteins, such as interleukin-12 (IL-12), have demonstrated considerable potential as robust tumor suppressors. However, their applications are limited due to a multitude of severe side effects.”
Video:
Doctors warn of rise in lung cancer among non-smokers
“One Triad woman was diagnosed at 30 years old. There are three warning signs that you should see a doctor.”
Treatment-Specific Biomarkers, Future of Research for Lung Cancer with Jonathan Spicer, MD, PhD
“In this Lungcast segment, Spicer spoke on several treatment-specific biomarkers for lung cancer and discussed the future of lung cancer therapy.”
My Choices News Update
by Lorren Sandt | February 12, 2024 | Weekly News | 0 Comments
Georgia State University Researcher Examines State of Warning Labels on Cannabis, Tobacco and Opioid Medications
“ATLANTA — A growing number of states have legalized recreational marijuana use, but a lack of consistency in warning consumers of potential harms threatens public health. That’s one of many takeaways from a review article authored by a Georgia State University School of Public Health researcher and her colleagues that examines the impact of warning labels on tobacco, cannabis and prescription opioids. The article appears in the early online edition of the journal Annual Review of Public Health.”
Harnessing the Power of Mindfulness for Heart Health: Promoting Adherence to the DASH Diet and Beyond
“Recent studies have uncovered intriguing links between mindfulness training and improved adherence to the DASH diet, a diet plan renowned for its cardiovascular benefits. This notable finding emphasizes the potential of mindfulness as a tool for fostering healthier dietary habits, particularly among those battling hypertension. The research offers invaluable insights into the interplay between mindfulness and heart health, shedding new light on the possible advantages of mindfulness practices for managing high blood pressure. The message is clear: adopting a mindful approach to eating could hold the key to better heart health.”
Harnessing the Power of Diaphragmatic Breathing for Stress Relief and Better Health
“In today’s fast-paced world, stress and anxiety have become pervasive issues affecting millions of people. While there are various coping mechanisms, one simple and effective method that often gets overlooked is diaphragmatic breathing. It’s a mindful breathing technique that can be practiced anytime, anywhere, and has been scientifically proven to lower stress and reduce feelings of anxiety.”
Study says long COVID makes exercise difficult, but a North Texas doctor says not impossible
“A recent study found long COVID can adversely affect your ability to exercise. And not just because of chronic fatigue. However, Dr. Salman Bhai, director of the neuromuscular center at the Institute for Exercise and Environmental Medicine at Texas Health Dallas, told KERA’s Sam Baker that with help, an exercise routine is still possible with long COVID.”
You Probably Can’t ‘Exercise Away’ the Calories in Sodas: Study
“Key Takeaways: Working out won’t eliminate the risk to heart health posed by sugary drinks. People consuming sugary drinks more than twice a week had a higher risk of heart disease, regardless of their physical activity levels. Artificially sweetened beverages were not associated with heart risk”
Does Your Blood Type Affect Your Heart Health? Yes, but Here’s the Full Story
“Certain blood types are associated with health problems like blood clotting, but that’s just one piece of the heart health puzzle.”
We asked. You answered. Here are your secrets to healthy aging
“In the 1960s and ’70s, The 2,000 Year-Old Man, was popular a comedy routine performed by Carl Reiner and Mel Brooks. Brooks played a 2,000 year-old man – apparently in terrific health – and Reiner, a modern man, would ask him questions, including if he’d share the secrets to his longevity. “The major thing is that I never ever touch fried food,” was Brooks’ response in one early recording. Also, “Never run for a bus; there will always be another,” and eat lots of nectarines. Not bad! Whether you’re 2,000 or 20, we’re all aging and we all have wisdom and experiences to share. That’s why NPR asked our listeners and readers to share their secrets to living a long and healthy life, as part of our new series, How to Thrive as You Age. To date we’ve received over 1,000 responses from readers and listeners ages 16 to 103.”
Weight-loss drugs aren’t a magic bullet. Lifestyle changes are key to lasting health
“The headlines are compelling, with phrases like, “The Obesity Revolution,” and “A new ‘miracle’ weight-loss drug really works.” The before-and-after pictures are inspiring. People who have struggled for decades to shed pounds are finally finding an effective strategy.”
Weekly News Update.
Caring Ambassadors Program provides 3 weekly news updates covering Lung Cancer News, Hepatitis C News, and My Choices© Update. Receive them delivered weekly to your inbox.
Lung Cancer Choices 6th Edition can be a useful tool for anyone who is caring for someone with lung cancer, but its primary focus is on the patient.
This book is suitable for both the newly diagnosed and those who have been living with lung cancer for some time.