CARING AMBASSADORS

Empowering People to be Ambassadors of their Own Health Since 1997.

LUNG CANCER PROGRAM


Monthly Pubmed Review

Monthly Pubmed Review of the Most Relevant Research on Lung Cancer
Literature Review,  June  2016

 

BASIC AND APPLIED SCIENCE, PRE-CLINICAL STUDIES

Polymorphism of rs9387478 correlates with overall survival in female nonsmoking patients with lung cancer. Han JF1,2, An SJ2, Su WM2, et al. Int J Biol Markers. 2016 May 28;31(2):e144-52. doi: 10.5301/jbm.5000180.
ROS1 in patients with lung cancer.

High Expression of Rab-like 3 (Rabl3) is Associated with Poor Survival of Patients with Non-Small Cell Lung Cancer via Repression of MAPK8/9/10-Mediated Autophagy. Zhang W1, Sun J2, Luo J3. Med Sci Monit. 2016 May 10;22:1582-8.

Shorter telomere length of T-cells in peripheral blood of patients with lung cancer. Qian Y1, Ding T1, Wei L2, Cao S3, Yang L1. Onco Targets Ther. 2016 May 4;9:2675-82. doi: 10.2147/OTT.S98488. eCollection 2016.

PAXIP1 potentiates the combination of WEE1 inhibitor AZD1775 and platinum agents in lung cancer. Jhuraney A1, Woods NT1, Wright G2, et al. Mol Cancer Ther. 2016 May 11. pii: molcanther.0182.2015. [Epub ahead of print]

SCREENING, DIAGNOSIS AND STAGING

Comprehensive Genomic Profiling Facilitates Implementation of the National Comprehensive Cancer Network Guidelines for Lung Cancer Biomarker Testing and Identifies Patients Who May Benefit From Enrollment in Mechanism-Driven Clinical Trials. Suh JH1, Johnson A2, Albacker L2, et al. Oncologist. 2016 May 5. pii: theoncologist.2016-0030. [Epub ahead of print]

Liquid Biopsy in Lung Cancer: A Perspective From Members of the Pulmonary Pathology Society. Sholl LM1, Aisner DL1, Allen TC1, et al. Arch Pathol Lab Med. 2016 May 19. [Epub ahead of print]

Prognostic Value of Volumetric Parameters on Staging and Posttreatment FDG PET/CT in Patients With Stage IV Non-Small Cell Lung Cancer. Lee JW1, Lee SM, Yun M, Cho A. Clin Nucl Med. 2016 May;41(5):347-53. doi: 10.1097/RLU.0000000000001126.

Electromagnetic Navigation Bronchoscopy-Guided Dye Marking for Thoracoscopic Resection of Pulmonary Nodules. Awais O1, Reidy MR1, Mehta K1, et al. Ann Thorac Surg. 2016 May 5. pii: S0003-4975(16)00224-1. doi: 10.1016/j.athoracsur.2016.02.040. [Epub ahead of print]

The International Association for the Study of Lung Cancer consensus statement on optimizing management of EGFR mutation positive non-small cell lung cancer: status in 2016. Tan DS1, Yom SS2, Tsao MS3, et al. J Thorac Oncol. 2016 May 20. pii: S1556-0864(16)30458-0. doi: 10.1016/j.jtho.2016.05.008. [Epub ahead of print]

Shared Medical Decision Making in Lung Cancer Screening: Experienced versus Descriptive Risk Formats. Fraenkel L1, Peters E2, Tyra S2, Oelberg D2. Med Decis Making. 2016 May;36(4):518-25. doi: 10.1177/0272989X15611083. Epub 2015 Oct 6.

CLINICAL TRIALS, COHORT STUDIES, PILOT STUDIES – NSCLC – SURGERY

Surgical Intervention Improves Survival for Metastatic Non-Small Cell Lung Cancer Patients. Shen H1, Cao Y, Li X, et al. Medicine (Baltimore). 2016 May;95(21):e3800. doi: 10.1097/MD.0000000000003800.

Cell cycle progression score is a marker for five-year lung cancer-specific mortality risk in patients with resected stage I lung adenocarcinoma. Eguchi T1,2, Kadota K3,4, Chaft J5, et al. Oncotarget. 2016 May 2. doi: 10.18632/oncotarget.9129. [Epub ahead of print]

Early and late recurrence after intentional limited resection for cT1aN0M0, non-small cell lung cancer: from a multi-institutional, retrospective analysis in Japan. Matsumura Y1, Yano M2, Yoshida J3, et al. Interact Cardiovasc Thorac Surg. 2016 May 25. pii: ivw125. [Epub ahead of print]

The Effects of Residential Segregation and Neighborhood Characteristics on Surgery and Survival in Patients with Early-Stage Non-Small Cell Lung Cancer. Johnson AM1, Johnson A2, Hines RB3, Bayakly R4. Cancer Epidemiol Biomarkers Prev. 2016 May;25(5):750-8. doi: 10.1158/1055-9965.EPI-15-1126.

CLINICAL TRIALS, COHORT STUDIES, PILOT STUDIES – NSCLC – CHEMOTHERAPY

Management of EGFR Mutation-Positive Non-Small Cell Lung Cancer. Lilenbaum RA1, Horn LA1. J Natl Compr Canc Netw. 2016 May;14(5 Suppl):672-4.

First-line treatment of advanced epidermal growth factor receptor (EGFR) mutation positive non-squamous non-small cell lung cancer. Greenhalgh J1, Dwan K, Boland A, Bates V, Vecchio F, Dundar Y, Jain P, Green JA. Cochrane Database Syst Rev. 2016 May 25;5:CD010383. doi: 10.1002/14651858.CD010383.pub2.

Time is Money: Hospital Costs Associated With Video-Assisted Thoracoscopic Surgery Lobectomies. Khullar OV1, Fernandez FG1, Perez S2, et al. Ann Thorac Surg. 2016 May 18. pii: S0003-4975(16)30125-4. doi: 10.1016/j.athoracsur.2016.03.024. [Epub ahead of print]

PD-L1 polymorphism can predict clinical outcomes of non-small cell lung cancer patients treated with first-line paclitaxel-cisplatin chemotherapy. Lee SY1,2, Jung DK3,4, Choi JE3,5, et al. Sci Rep. 2016 May 16;6:25952. doi: 10.1038/srep25952.

CLINICAL TRIALS, COHORT STUDIES, PILOT STUDIES – NSCLC – RADIOTHERAPY

“Even if I Don’t Remember, I Feel Better”: A Qualitative Study of Early Stage Non-Small Cell Lung Cancer Patients Undergoing Stereotactic Body Radiotherapy or Surgery. Golden SE1, Thomas CR Jr2, Deffebach ME3,4, Sukumar MS5, Schipper PH6, Tieu BH7, Kee AY8, Tsen AC9, Slatore CG10,11; Early Stage Lung Cancer Comparative Effectiveness Research Consortium. Ann Am Thorac Soc. 2016 May 16. [Epub ahead of print]

Establishing the feasibility of the dosimetric compliance criteria of RTOG 1308: phase III randomized trial comparing overall survival after photon versus proton radiochemotherapy for inoperable stage II-IIIB NSCLC. Giaddui T1, Chen W2, Yu J2, et al. Radiat Oncol. 2016 May 4;11(1):66. doi: 10.1186/s13014-016-0640-8.

Isolated Nodal Failure after Stereotactic Body Radiotherapy for Lung Cancer: The Role for Salvage Mediastinal Radiotherapy. Ward MC1, Oh SC2, Pham YD2, Woody NM2, Marwaha G3, Videtic GM2, Stephans KL2. J Thorac Oncol. 2016 May 17. pii: S1556-0864(16)30452-X. doi: 10.1016/j.jtho.2016.05.003. [Epub ahead of print]

Statistical Determination of the Gating Windows for Respiratory-Gated Radiotherapy Using a Visible Guiding System. Oh SA1,2, Yea JW1,2,3, Kim SK1,2,3. PLoS One. 2016 May 26;11(5):e0156357. doi: 10.1371/journal.pone.0156357. eCollection 2016.

Can we predict the development of serious adverse events (SAEs) and early treatment termination in elderly non-small cell lung cancer (NSCLC) patients receiving platinum-based chemotherapy? Kato T1, Morise M2, Ando M3, et al. J Cancer Res Clin Oncol. 2016 Jul;142(7):1629-40. doi: 10.1007/s00432-016-2170-z. Epub 2016 May 11.

Feasibility and efficacy of helical intensity-modulated radiotherapy for stage III non-small cell lung cancer in comparison with conventionally fractionated 3D-CRT. He J1, Huang Y1, Chen Y1, Shi S1, Ye L1, Hu Y1, Zhang J1, Zeng Z1. J Thorac Dis. 2016 May;8(5):862-71. doi: 10.21037/jtd.2016.03.46.

A feasibility study of dynamic adaptive radiotherapy for nonsmall cell lung cancer. Kim M1, Phillips MH2. Med Phys. 2016 May;43(5):2153. doi: 10.1118/1.4945023.

CLINICAL TRIALS, COHORT STUDIES, PILOT STUDIES – NSCLC – OTHER

CLINICAL TRIALS, COHORT STUDIES, PILOT STUDIES – SMALL CELL LUNG CANCER (SCLC)

Prognostic impact of a 3-MicroRNA signature in cytological samples of small cell lung cancer. Mancuso G1, Bovio E2, Rena O3, et al. Cancer Cytopathol. 2016 May 6. doi: 10.1002/cncy.21729. [Epub ahead of print]

Vismodegib or cixutumumab in combination with standard chemotherapy for patients with extensive-stage small cell lung cancer: A trial of the ECOG-ACRIN Cancer Research Group (E1508). Belani CP1, Dahlberg SE2, Rudin CM3, et al. Cancer. 2016 May 10. doi: 10.1002/cncr.30062. [Epub ahead of print]

Increased Biological Effective Dose of Radiation Correlates with Prolonged Survival of Patients with Limited-Stage Small Cell Lung Cancer: A Systematic Review. Zhu L1,2, Zhang S1,2, et al. PLoS One. 2016 May 26;11(5):e0156494. doi: 10.1371/journal.pone.0156494. eCollection 2016.

A New Score for Estimating Survival After Definitive Radiochemotherapy of Limited Disease Small Cell Lung Cancers. Rades D1, Kaesmann L2, Janssen S2,3, Schild SE4. Lung. 2016 May 2. [Epub ahead of print]

Patient-derived xenografts faithfully replicated clinical outcome in a phase II co-clinical trial of arsenic trioxide in relapsed small cell lung cancer. Owonikoko TK1, Zhang G2, Kim HS3, et al. J Transl Med. 2016 May 3;14(1):111. doi: 10.1186/s12967-016-0861-5.

PALLIATIVE AND SUPPORTIVE CARE

Palliative Care for Patients Dying in the Intensive Care Unit with Chronic Lung Disease Compared with Metastatic Cancer. Brown CE1, Engelberg RA1, Nielsen EL1, Curtis JR1. Ann Am Thorac Soc. 2016 May;13(5):684-9. doi: 10.1513/AnnalsATS.201510-667OC.

Integrated Palliative Care and Oncologic Care in Non-Small-Cell Lung Cancer. Chandrasekar D1, Tribett E2, Ramchandran K3. Curr Treat Options Oncol. 2016 May;17(5):23. doi: 10.1007/s11864-016-0397-1.

The Utility of Exercise Testing in Patients with Lung Cancer. Ha D1, Mazzone PJ2, Ries AL3, Malhotra A3, Fuster M4. J Thorac Oncol. 2016 May 5. pii: S1556-0864(16)30402-6. doi: 10.1016/j.jtho.2016.04.021. [Epub ahead of print]

Lower Pectoralis Muscle Area is Associated with a Worse Overall Survival in Non- Small Cell Lung Cancer. Kinsey CM1, San Jose Estepar R2, Van der Velden J3, Cole BF4, Christiani DC5, Washko GR6. Cancer Epidemiol Biomarkers Prev. 2016 May 19. pii: cebp.1067.2015. [Epub ahead of print]

Chronic condition clusters and functional impairment in older cancer survivors: a population-based study. Kenzik KM1, Kent EE2, Martin MY3, Bhatia S4, Pisu M5. J Cancer Surviv. 2016 May 27. [Epub ahead of print]

Relationship between Efficacy Outcomes and Weight Gain during Treatment of Advanced, Nonsquamous, Non-small Cell Lung Cancer Patients. Patel JD1, Pereira JR2, Chen J3, et al. Ann Oncol. 2016 May 23. pii: mdw211. [Epub ahead of print]

Cachexia among US cancer patients. Arthur ST1, Van Doren BA1, Roy D1, Noone JM1, Zacherle E1, Blanchette CM1. J Med Econ. 2016 May 11:1-7. [Epub ahead of print]

The Association of Chemotherapy-Induced Peripheral Neuropathy Symptoms and the Risk of Falling. Kolb NA1, Smith AG1, Singleton JR1, Beck SL2, Stoddard GJ3, Brown S1, Mooney K2. JAMA Neurol. 2016 May 16. doi: 10.1001/jamaneurol.2016.0383. [Epub ahead of print]

Lower Patient Ratings of Physician Communication Are Associated With Unmet Need for Symptom Management in Patients With Lung and Colorectal Cancer. Walling AM1, Keating NL2, Kahn KL2, et al. J Oncol Pract. 2016 Jun;12(6):e654-69. doi: 10.1200/JOP.2015.005538. Epub 2016 May 24.

Factors associated with depression and anxiety symptoms in family caregivers of patients with incurable cancer. Nipp RD1, El-Jawahri A2, Fishbein JN3, et al. Ann Oncol. 2016 May 13. pii: mdw205. [Epub ahead of print]

Cost Analysis of a Randomized Trial of Early Palliative Care in Patients with Metastatic Nonsmall-Cell Lung Cancer. Greer JA1, Tramontano AC1, McMahon PM1, et al. J Palliat Med. 2016 May 11. [Epub ahead of print]

The effect of chemotherapy-induced anemia on dose reduction and dose delay. Family L1, Xu L1, Xu H2, Cannavale K1, Sattayapiwat O1, Page JH2, Bohac C2, Chao C3. Support Care Cancer. 2016 May 11. [Epub ahead of print]

COMPLEMENTARY & ALTERNATIVE THERAPY

Bergamottin isolated from Citrus bergamia exerts in vitro and in vivo antitumor activity in lung adenocarcinoma through the induction of apoptosis, cell cycle arrest, mitochondrial membrane potential loss and inhibition of cell migration and invasion. Wu HJ1, Wu HB1, Zhao YQ1, Chen LJ1, Zou HZ1. Oncol Rep. 2016 May 23. doi: 10.3892/or.2016.4833. [Epub ahead of print]

Complementary and Alternative Medicine Use at a Comprehensive Cancer Center. Luo Q1, Asher GN2. Integr Cancer Ther. 2016 May 4. pii: 1534735416643384. [Epub ahead of print]

The Efficacy of Traditional Chinese Herbal Medicine in the Treatment of EGFR Mutated Stage IV Pulmonary Adenocarcinoma Patients Who Received First-Line EGFR-TKI Treatment. Hung HY1, Tseng YH2, Liao CM1, Chen SY1, Wu TP1, Lee YC3, Chen YM4. Integr Cancer Ther. 2016 May 5. pii: 1534735416645181. [Epub ahead of print]

In Vivo Anti-Cancer Mechanism of Low-Molecular-Weight Fucosylated Chondroitin Sulfate (LFCS) from Sea Cucumber Cucumaria frondosa. Liu X1,2, Liu Y3,4, Hao J5,6, et al. Molecules. 2016 May 12;21(5). pii: E625. doi: 10.3390/molecules21050625.

Potential Combinational Anti-Cancer Therapy in Non-Small Cell Lung Cancer with Traditional Chinese Medicine Sun-Bai-Pi Extract and Cisplatin. Tseng CY1, Lin CH2, Wu LY3, Wang JS2, Chung MC2, Chang JF2, Chao MW2. PLoS One. 2016 May 12;11(5):e0155469. doi: 10.1371/journal.pone.0155469. eCollection 2016.

 

MISCELLANEOUS WORKS

Typical Time to Treatment of Patients With Lung Cancer in a Multisite, US-Based Study. Vidaver RM1, Shershneva MB1, Hetzel SJ1, Holden TR1, Campbell TC2. J Oncol Pract. 2016 Jun;12(6):e643-53. doi: 10.1200/JOP.2015.009605. Epub 2016 May 3.

Nicotine-Mediated Regulation of Nicotinic Acetylcholine Receptors in Non-Small Cell Lung Adenocarcinoma by E2F1 and STAT1 Transcription Factors. Schaal C1,2, Chellappan S1. PLoS One. 2016 May 26;11(5):e0156451. doi: 10.1371/journal.pone.0156451. eCollection 2016.

Former smokers with non-small-cell lung cancers: a comprehensive investigation of clinicopathologic characteristics, oncogenic drivers, and prognosis. Zheng S1,2, Wang R3, Zhang Y1,2,  et al. Cancer Med. 2016 May 26. doi: 10.1002/cam4.764. [Epub ahead of print]

Early impact of Medicare accountable care organizations on cancer surgery outcomes. Herrel LA1, Norton EC2,3,4, Hawken SR1, Ye Z1, Hollenbeck BK1, Miller DC1. Cancer. 2016 May 24. doi: 10.1002/cncr.30111. [Epub ahead of print] Society.

Pre-existing diabetes and lung cancer prognosis. Luo J1, Hendryx M2, Qi L3, Ho GY4, Margolis KL5. Br J Cancer. 2016 May 19. doi: 10.1038/bjc.2016.141. [Epub ahead of print]

Disparities in cancer treatment among patients infected with the human immunodeficiency virus. Suneja G1, Lin CC2, Simard EP3, Han X2, Engels EA4, Jemal A2. Cancer. 2016 May 17. doi: 10.1002/cncr.30052. [Epub ahead of print]

The American Cancer Society challenge goal to reduce US cancer mortality by 50% between 1990 and 2015: Results and reflections. Byers T1, Wender RC2, Jemal A3, Baskies AM4, Ward EE5, Brawley OW6. CA Cancer J Clin. 2016 May 13. doi: 10.3322/caac.21348. [Epub ahead of print]

Characteristics of Smoking Patients with Lung Cancer with Emphysematous Bullae. Iwama E1, Okamoto I2, Yabuuchi H3, et al. J Thorac Oncol. 2016 May 7. pii: S1556-0864(16)30405-1. doi: 10.1016/j.jtho.2016.04.024. [Epub ahead of print]

 

 

Caring Ambassadors Program, Inc. | P.O. Box 1748 | Oregon City, OR 97045 | 503-632-9032 | 503-632-9038 (Fax)